We are in ath the Ghent University Hospital at the moment. There was a good response at first, but, after the tumour resection all the metastasis in his bones began to grow, his bone marrow was invaded and he developed brain mets too… Since then we had additional TVD, MTX and ICE. Non of those were successful, leading the doctors to believe the tumour is resistent to all chemo they throw at it. The disease is progressing.
The BEACON trial that will start next week will be Bevacizumab, Irinotecan and/or Temozolomide. The doctors do not expect this will cure him, but it will stretch out the remaining time we have.
Tumour biology did not reveal any abnormalities. No MYCN, nothing really. The doctors are quite stumped by this one.
Just out of interest, beside MYCN, what can they test for?