Curcumin formula shows promise against treatment-resistant childhood cancer


(Alexey) #1

May be in one day it will be a standard therapy

In the study, researchers loaded Cerium oxide nanoparticles with curcumin and coated them with dextran to test in cell lines of a high-risk form of neuroblastoma, known as MYCN-amplified, as well as non-amplified neuroblastoma. This formulation induced substantial cell death in neuroblastoma cells while producing no or only minor toxicity in healthy cells. Overall, the nano-therapeutic treatments showed a more pronounced effect in MYCN-amplified cells, which are traditionally more resistant to drug therapies.

http://pubs.rsc.org/en/content/articlelanding/2017/nr/c7nr02770b#!divAbstract